{"schema_version":"secwatch.filing_event.v1","accession":"0001609550-25-000046","form_type":"8-K","ticker":"INSP","cik":"0001609550","company_name":"Inspire Medical Systems, Inc.","filed_at":"2025-10-10T23:59:59+00:00","discovered_at":"2026-05-14T18:02:39.911462+00:00","generated_at":"2026-05-17T04:04:44.905189+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"Inspire V clinical data shows superior efficacy, adherence, and reduced surgical times; AHI cut from 34.4 to 8.3","bullets":["Singapore study (44 patients): Inspire V IPOP 87.1% vs Inspire IV 79.4%, exceeding non-inferiority margin of 4.6%.","Median AHI reduced from 34.4 to 8.3 events/hour at 6 months for 37 Singapore patients.","US limited market release (101 patients): no serious adverse events; 100% therapy usage at 60 days; average adherence 6.8 hrs/night.","AHI for first 34 US patients dropped from 30 to 4.5 events/hour; average stimulation amplitude 1.7V.","20% reduction in surgical times; average implant time 34.5 minutes at one site; new internal respiratory sensing eliminates pressure lead."],"urls":{"canonical":"https://secwatch.observer/filing/0001609550-25-000046","json":"https://secwatch.observer/filing/0001609550-25-000046.json","markdown":"https://secwatch.observer/filing/0001609550-25-000046.md","text":"https://secwatch.observer/filing/0001609550-25-000046.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1609550/000160955025000046/0001609550-25-000046-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1609550/000160955025000046/insp-20251010.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T04:04:44.905189+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}