secwatch.observer — SEC 8-K summary ====================================== Issuer: Caribou Biosciences, Inc. (CRBU) CIK: 0001619856 Form: 8-K Filed at: 2025-04-24T23:59:59+00:00 Accession: 0001619856-25-000023 Event type: other_material Sentiment: negative Materiality: 0.75 Item codes: 2.02, 2.05, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Caribou cuts 32% workforce, discontinues lupus/AML trials, cash runway to H2 2027 -------------------------------------------------------------------------------- - Workforce reduction of 47 employees (~32%), expected completion by Q2 2025. - Preliminary cash, equivalents & marketable securities of $212.5M as of March 31, 2025. - Discontinued GALLOP (lupus), AMpLify (AML) trials & preclinical research to focus on CB-010 & CB-011. - Estimated restructuring costs of $2.5-3.5M, primarily severance and trial wind-down. - Cash runway extended one year to H2 2027; CB-010 & CB-011 data readouts planned for H2 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1619856/000161985625000023/0001619856-25-000023-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1619856/000161985625000023/crbu-20250424.htm HTML page: https://secwatch.observer/filing/0001619856-25-000023 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer