other material
confidence high
sentiment positive
materiality 0.85
Aurinia reports positive 3-year AURORA 2 data for LUPKYNIS; no new safety signals
Aurinia Pharmaceuticals Inc.
- eGFR stable over 36 months; +2.7 mL/min vs control from baseline.
- Serious AE rates: 19% voclosporin vs 24% control; 0 deaths in voclosporin arm vs 4 in placebo.
- Mean UPCR lower in voclosporin group at all time points over 3 years.
- Withdrawal rate: 12.9% voclosporin vs 15.0% control; drug well tolerated.
- AURORA 2 enrolled 216 LN patients; 90 voclosporin and 78 control completed 36 months.