Prime Medicine adopts Second Amended and Restated Bylaws with updated stockholder proposal procedures

Prime Medicine, Inc.

Board adopted Second A&R Bylaws effective May 17, 2024, superseding prior bylaws.
Revises advance notice procedures for stockholder proposals and director nominations.
Addresses universal proxy rules; requires compliance with Rule 14a-19 for non-Board nominees.
Clarifies Board meeting procedures including postponing, rescheduling, canceling stockholder meetings.
Updates routine, technical, and non-substantive provisions.

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