other material
confidence high
sentiment neutral
materiality 0.55
Instil Bio and ImmuneOnco outline global registrational strategy for SYN-2510 in NSCLC and TNBC
Instil Bio, Inc.
- Global registrational strategy for SYN-2510/IMM2510 in front-line NSCLC and TNBC announced.
- Phase 1b/2 chemo combo in front-line NSCLC expected to start late 2024 in China; US IND submission for SYN-2510 targeted late 2024 for Phase 2 monotherapy in second-line NSCLC.
- Phase 1b/2 chemo combo in front-line TNBC expected to start early 2025 in China; potential global Phase 3 trials after proof-of-concept.
- US Phase 2 monotherapy trial in second-line NSCLC expected to support efficient enrollment of global Phase 3 studies.