other material
confidence high
sentiment positive
materiality 0.60
Aquestive presents Anaphylm data showing consistent PK/PD regardless of film movement
Aquestive Therapeutics, Inc.
- 87.5% of subjects had no film movement; 12.5% showed movement with no significant PK/PD impact.
- Geometric mean Cmax: 351.14 pg/mL (movement) vs 490.27 pg/mL (no movement); p=0.49.
- Median Tmax was 12 minutes for both groups; comparable to epinephrine injection.
- Data supports Anaphylm as a potential needle-free epinephrine option for anaphylaxis if FDA-approved.