other material
confidence high
sentiment negative
materiality 0.65
Foghorn discontinues FHD-286 in AML; prioritizes pipeline and Lilly collaboration
Foghorn Therapeutics Inc.
- FHD-286 + decitabine showed objective responses in Phase 1 but efficacy threshold not met for continued standalone development.
- Company evaluating partnerships/ISTs for FHD-286; independent development halted.
- Priorities: proprietary CBP, EP300, ARID1B programs and Lilly collaboration including SMARCA2 inhibitor FHD-909.
- Cash of $267.4M as of Sept 30, 2024; runway into 2027.