{"schema_version":"secwatch.filing_event.v1","accession":"0001628280-25-004637","form_type":"8-K","ticker":"ARWR","cik":"0000879407","company_name":"ARROWHEAD PHARMACEUTICALS, INC.","filed_at":"2025-02-10T23:59:59+00:00","discovered_at":"2026-05-14T18:03:06.627673+00:00","generated_at":"2026-05-27T00:42:27.706941+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"Arrowhead Q1 net loss $173M; $825M Sarepta deal & plozasiran NDA accepted","bullets":["Net loss of $173M ($1.39 diluted EPS), revenue $2.5M, operating loss $161.4M.","Sarepta collaboration: $825M upfront ($500M cash + $325M equity at $27.25/share, 35% premium), plus $250M over 5 years, up to $10B milestones.","Plozasiran NDA for familial chylomicronemia syndrome accepted; PDUFA date Nov 18, 2025.","Phase 3 PALISADE met primary endpoint; plozasiran reduced triglycerides up to 86% and acute pancreatitis.","Cash & investments $552.9M; company funded into 2028; obesity programs (ARO-INHBE, ARO-ALK7) entering Phase 1."],"urls":{"canonical":"https://secwatch.observer/filing/0001628280-25-004637","json":"https://secwatch.observer/filing/0001628280-25-004637.json","markdown":"https://secwatch.observer/filing/0001628280-25-004637.md","text":"https://secwatch.observer/filing/0001628280-25-004637.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/879407/000162828025004637/0001628280-25-004637-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/879407/000162828025004637/arwr-20250210.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-27T00:42:27.706941+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}