secwatch.observer — SEC 8-K summary ====================================== Issuer: Prime Medicine, Inc. (PRME) CIK: 0001894562 Form: 8-K Filed at: 2025-02-28T23:59:59+00:00 Accession: 0001628280-25-008873 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Prime Medicine reports FY2024 net loss $195.9M; cash $204.5M; PM359 data in 2025 -------------------------------------------------------------------------------- - Net loss $195.9M for FY2024 vs $198.1M in FY2023; R&D expenses $155.3M. - Cash, equivalents, and investments $204.5M at Dec 31, 2024, up from $135.2M. - Initial clinical data from PM359 Phase 1/2 for p47 phox CGD expected in 2025. - IND/CTA filing for PM577 (Wilson's Disease) planned for first half of 2026. - Cash runway expected into first half of 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1894562/000162828025008873/0001628280-25-008873-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1894562/000162828025008873/prme-20250228.htm HTML page: https://secwatch.observer/filing/0001628280-25-008873 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer