---
schema_version: "secwatch.filing_event.v1"
accession: "0001628280-25-022871"
form_type: "8-K"
ticker: "LNTH"
cik: "0001521036"
company_name: "Lantheus Holdings, Inc."
filed_at: "2025-05-07T23:59:59+00:00"
generated_at: "2026-05-22T07:49:51.993265+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.8
calibrated_materiality_score: 0.8
confidence: "high"
source: SEC EDGAR
---

# Lantheus Q1 adj EPS $1.53 (-9.5% YoY); cuts FY25 adj EPS guidance to $6.60-$6.70 from $7.00-$7.20

## Summary
- Q1 revenue $372.8M (+0.8% YoY); GAAP EPS $1.02 vs $1.87; adj EPS $1.53 vs $1.69.
- PYLARIFY sales $257.7M (-0.5%); DEFINITY $79.2M (+3.5%).
- FY2025 revenue guidance narrowed to $1.550B-$1.585B; adj EPS guidance lowered to $6.60-$6.70 from $7.00-$7.20.
- Closed Evergreen Theragnostics; agreed to acquire Life Molecular Imaging (Q2); announced SPECT divestiture to SHINE (by year-end).
- MK-6240 met endpoints in pivotal studies; NDA planned Q3 2025. PNT2002 will not proceed to NDA.

## SEC filing metadata
- accession: 0001628280-25-022871
- form_type: 8-K
- ticker: LNTH
- cik: 0001521036
- company_name: Lantheus Holdings, Inc.
- filed_at: 2025-05-07T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.8
- calibrated_materiality_score: 0.8
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1521036/000162828025022871/0001628280-25-022871-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1521036/000162828025022871/lnth-20250507.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001628280-25-022871
- JSON: https://secwatch.observer/filing/0001628280-25-022871.json
- Plain text: https://secwatch.observer/filing/0001628280-25-022871.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.