secwatch.observer — SEC 8-K summary ====================================== Issuer: CRESCENT BIOPHARMA, INC. (CBIO) CIK: 0001253689 Form: 8-K Filed at: 2025-11-06T23:59:59+00:00 Accession: 0001628280-25-049865 Event type: earnings Sentiment: neutral Materiality: 0.55 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Crescent Bio Q3 net loss $24.6M; cash $133.3M; CR-001 IND on track ------------------------------------------------------------------ - Net loss of $24.6M ($1.27 per share) for Q3 2025; R&D expense $20.3M, G&A $5.5M. - Cash position $133.3M as of Sept 30, 2025, expected to fund operations through 2027. - IND submission for CR-001 (PD-1 x VEGF bispecific) on track for Q4 2025; Phase 1 start Q1 2026. - Preclinical data for CR-001 presented at SITC showing cooperative pharmacology and anti-tumor activity. - ADC program CR-002 IND submission expected mid-2026; CR-003 also advancing. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1253689/000162828025049865/0001628280-25-049865-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1253689/000162828025049865/cbio-20251106.htm HTML page: https://secwatch.observer/filing/0001628280-25-049865 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer