Charles River Labs reports improving DSA book-to-bill trends, encouraged by momentum since mid-2025

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

DSA net book-to-bill has improved each month since Q3 2025 started.
Management cites positive momentum and upward trends from mid-2025 onward.
Seasonality around holidays and early January may affect near-term proposal and booking activity.
Update provided at Evercore 8th Annual Healthcare Conference on December 3, 2025.

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