other material
confidence high
sentiment positive
materiality 0.75
Vir Bio: 88% HDV RNA undetectable at Week 96 in combo arm; cash ~$781M, runway to Q4 2027
Vir Biotechnology, Inc.
- Phase 2 SOLSTICE: 88% (21/24) of combo arm achieved undetectable HDV RNA at Week 96 vs 46% (11/24) monotherapy.
- No grade 3+ treatment-related AEs in combo arm; generally mild/moderate and transient.
- Cash, cash equivalents & investments ~$781M at Dec 31, 2025; runway extended into Q4 2027 via Norgine deal.
- ECLIPSE 1 Phase 3 topline data expected Q4 2026; ECLIPSE 2/3 top-line in Q1 2027.
- VIR-5500 Phase 1 data in prostate cancer to be presented at ASCO GU Feb 2026.