other material
confidence high
sentiment positive
materiality 0.75
C4 Therapeutics outlines milestones through 2028; cemsidomide Phase 2 trial on track for Q1 2026
C4 Therapeutics, Inc.
- Cemsidomide Phase 2 MOMENTUM trial to begin Q1 2026; recommended Phase 2 dose 100 µg.
- Phase 1b combination with elranatamab to start Q2 2026; potential accelerated approval path for 4L+ by end 2028.
- Phase 1 data: 40% ORR at 75 µg, 53% ORR at 100 µg in heavily pretreated multiple myeloma patients.
- Cash runway to end 2028 provides funding through key value inflection points including NDA submission.
- Internal discovery strategy targeting inflammation and neurodegeneration; up to 3 IND applications by end 2028.