secwatch / observer
8-K filed March 19, 2026, 7:59 PM ET ticker SNTI CIK 0001854270
other material confidence high sentiment neutral materiality 0.55

Senti Biosciences cuts leased space 50% to 45,955 sq ft, amends sublease with GeneFab

Senti Biosciences, Inc.

Key facts

Extracted from this filing and checked against the source text.

Material Agreements SEC 8-K Item 1.01/1.02 confidence 0.9

Senti Biosciences, Inc. amended First Amendment to Sublease with GeneFab, LLC valued at subleased premises reduced to ~45,955 rentable square feet; base rent, operating expenses, taxes and (effective 2025-09-01).

Action
amendment
Agreement
lease
Counterparty
GeneFab, LLC
Value
subleased premises reduced to ~45,955 rentable square feet; base rent, operating expenses, taxes and
Effective
2025-09-01
Exact text from the filing
On March 17, 2026, the Company entered into a First Amendment to Sublease (the “Sublease Amendment”), which amended and restated that certain Sublease Agreement dated August 7, 2023 (the “Original Sublease Agreement” and the Original Sublease Agreement as amended by the Sublease Amendment, the “Amended Sublease”) by and between the Company, as sublandlord, and GeneFab, LLC (“GeneFab”) as subtenant. Pursuant to the Sublease Amendment, which was effective as of the Effective Date, the subleased premises were reduced to approximately 45,955 rentable square feet as of the Effective Date.
View on SEC.gov
Material Agreements SEC 8-K Item 1.01/1.02 confidence 0.9

Senti Biosciences, Inc. amended First Amendment to Landlord's Consent to Sublease with 1430 South Loop Owner, LLC and GeneFab, LLC valued at Landlord consented to Sublease Amendment in consideration for $1.0 million Reduction Fee (effective 2025-09-01).

Action
amendment
Counterparty
1430 South Loop Owner, LLC and GeneFab, LLC
Value
Landlord consented to Sublease Amendment in consideration for $1.0 million Reduction Fee
Effective
2025-09-01
Exact text from the filing
On March 17, 2026, the Company entered into a First Amendment to Landlord’s Consent to Sublease (the “Consent Amendment”) among the Company, the Landlord and GeneFab, which was effective as of the Effective Date. Pursuant to the Consent Amendment, the Landlord consented to the Sublease Amendment in consideration for the payment by the Company or GeneFab of $1.0 million to the Landlord (the “Reduction Fee”).
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Material Agreements SEC 8-K Item 1.01/1.02 confidence 0.9

Senti Biosciences, Inc. amended First Amendment to Lease with 1430 South Loop Owner, LLC valued at reduction of leased premises from ~91,910 to ~45,955 rentable square feet; monthly base rent reduced (effective 2025-09-01).

Action
amendment
Agreement
lease
Counterparty
1430 South Loop Owner, LLC
Value
reduction of leased premises from ~91,910 to ~45,955 rentable square feet; monthly base rent reduced
Effective
2025-09-01
Exact text from the filing
On March 17, 2026, Senti Biosciences, Inc. (the “Company”) entered into a First Amendment to Lease (the “Lease Amendment”), which amended that certain Research and Development and Laboratory Lease Agreement dated June 3, 2021 (the “Original Lease Agreement” and the Original Lease Agreement as amended by the Lease Amendment, the “Amended Lease”) by and between the Company and 1430 South Loop Owner, LLC (the “Landlord”) for the Company’s premises located at 1430 Harbor Bay Parkway, Alameda, California. Pursuant to the Lease Amendment, which is effective as of September 1, 2025 (the “Effective Date”), the Company has agreed to a reduction of the leased premises from approximately 91,910 rentable square feet to approximately 45,955 rentable square feet as of the Effective Date.
View on SEC.gov
Material Agreements SEC 8-K Item 1.01/1.02 confidence 0.9

Senti Biosciences, Inc. entered into Letter Agreement with GeneFab, LLC valued at outstanding base rent of $1,374,005 may be satisfied via cash prepayment credit for work or services (effective 2025-09-01).

Action
entry
Counterparty
GeneFab, LLC
Value
outstanding base rent of $1,374,005 may be satisfied via cash prepayment credit for work or services
Effective
2025-09-01
Exact text from the filing
On March 17, 2026, the Company entered into a letter agreement with GeneFab (the “Letter Agreement”), effective as of the Effective Date. The Letter Agreement provides, among other things, that the outstanding base rent of $1,374,005 owed by GeneFab to the Company may be satisfied, in whole or in part, through a cash prepayment credit to be applied toward work or services to be performed by GeneFab for the Company under a separate arrangement, that the Company may access such prepayment credit as of the Effective Date and that any unpaid portion must be paid in immediately available funds by September 1, 2026.
View on SEC.gov

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Senti Biosciences, Inc. filing history →

Source: SEC EDGAR
accession 0001628280-26-019789
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