secwatch.observer — SEC 8-K summary ====================================== Issuer: CRESCENT BIOPHARMA, INC. (CBIO) CIK: 0001253689 Form: 8-K Filed at: 2026-04-29T23:59:59+00:00 Accession: 0001628280-26-028386 Event type: earnings Sentiment: negative Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Crescent Biopharma Q1 net loss $23.3M; cash $189.2M funds ops into 2028 ----------------------------------------------------------------------- - Net loss $23.3M ($0.70/sh) vs $15.1M ($19.63/sh) in Q1 2025; revenue $1.0M from Kelun-Biotech license. - R&D expenses $17.9M (up 69% YoY) on CR-001/CR-002 development; G&A $7.9M (up 119% YoY). - Cash $189.2M as of March 31, 2026; expected to fund operations into 2028. - CR-001 ASCEND trial enrollment ongoing; proof-of-concept data expected Q1 2027. - CR-002 IND submission on track for mid-2026; clinic entry H2 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1253689/000162828026028386/0001628280-26-028386-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1253689/000162828026028386/cbio-20260429.htm HTML page: https://secwatch.observer/filing/0001628280-26-028386 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer