secwatch.observer — SEC 8-K summary ====================================== Issuer: RHYTHM PHARMACEUTICALS, INC. (RYTM) CIK: 0001649904 Form: 8-K Filed at: 2026-08-04T11:49:13+00:00 Accession: 0001628280-26-052170 Event type: earnings Sentiment: positive Materiality: 0.75 Item codes: 2.02, 7.01, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Rhythm Pharma Q2 revenue $71.3M; RM-718 shows -11.6% BMI reduction in HO ------------------------------------------------------------------------ - Q2 2026 IMCIVREE revenue $71.3M, up 19% sequentially; U.S. revenue $51.0M (+38% QoQ). - Over 400 patient start forms for IMCIVREE in acquired HO since FDA approval in March 2026. - RM-718 Phase 2: -11.6% mean BMI reduction at 16 weeks (n=7) in acquired HO, comparable to setmelanotide. - Net loss $(50.4)M ($(0.73)/share) vs $(48.0)M ($(0.75)/share) in Q2 2025. - Cash $330.9M; FY 2026 Non-GAAP OpEx guidance $363M-$397M. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1649904/000162828026052170/0001628280-26-052170-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1649904/000162828026052170/rytm-20260804.htm HTML page: https://secwatch.observer/filing/0001628280-26-052170 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer