{"schema_version":"secwatch.filing_event.v1","accession":"0001628280-26-054330","form_type":"8-K","ticker":"LYEL","cik":"0001806952","company_name":"Lyell Immunopharma, Inc.","filed_at":"2026-08-06T20:14:09+00:00","discovered_at":"2026-08-06T20:16:00.464510+00:00","generated_at":"2026-08-06T20:18:37.080104+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Lyell Immunopharma Q2 2026 net loss $44.8M; ronde-cel pivotal data expected mid-2027","bullets":["Net loss of $44.8M for Q2 2026 vs $42.7M in Q2 2025; non-GAAP net loss $40.6M.","Cash, equivalents and marketable securities $228.0M as of June 30, 2026, providing runway into Q3 2027.","PiNACLE trial for ronde-cel in 3L+ LBCL on track; additional data H2 2026, pivotal data mid-2027, BLA submission H2 2027.","LYL273 safety update: GI prophylaxis reduced Grade ≥2 diarrhea/colitis from 55% to 10%; Phase 1 trial amended to Phase 1/2 design.","R&D expenses $39.5M, up $4.7M YoY due to increased clinical trial activity."],"urls":{"canonical":"https://secwatch.observer/filing/0001628280-26-054330","json":"https://secwatch.observer/filing/0001628280-26-054330.json","markdown":"https://secwatch.observer/filing/0001628280-26-054330.md","text":"https://secwatch.observer/filing/0001628280-26-054330.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1806952/000162828026054330/0001628280-26-054330-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1806952/000162828026054330/lyel-20260806.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-08-06T20:18:37.080104+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}