other material
confidence high
sentiment positive
materiality 0.60
Precision BioSciences doses first patient in Phase 1/2 FUNCTION-DMD gene editing trial
PRECISION BIOSCIENCES INC
- First patient dosed with PBGENE-DMD, first clinical gene-editing program for DMD, at Arkansas Children's Hospital.
- PBGENE-DMD excises exons 45-55 to restore near full-length dystrophin; applicable to up to 60% of DMD patients.
- Trial enrolling ambulatory DMD patients aged 2-7 with mutations between exons 45-55; initial safety data expected by year-end 2026.
- PBGENE-DMD is wholly owned in vivo program using ARCUS platform; aims to durably improve function.