earnings
confidence high
sentiment positive
materiality 0.75
Spyre Q4 2023 net loss $63.2M; cash $339.6M; pipeline on track with SPY001 FIH H1 2024
Spyre Therapeutics, Inc.
2023-FY EPS reported
-$49.12
revenue$886,000
- Net loss $63.2M in Q4 2023 vs $18.8M in Q4 2022; cash $339.6M as of Dec 31, 2023.
- Raised $180M gross from private placement; cash runway into H2 2026.
- SPY001 anti-α4β7 shows 22-day half-life (3x vedolizumab); FIH studies expected H1 2024 with interim data year-end.
- SPY002 anti-TL1A candidates nominated; preclinical half-life 24 days (2-3x clinical-stage); FIH in H2 2024.
- Appointed CEO Cameron Turtle and board member Mark McKenna; name changed to Spyre Therapeutics.