---
schema_version: "secwatch.filing_event.v1"
accession: "0001641172-25-002752"
form_type: "8-K"
ticker: null
cik: "0001811623"
company_name: "PaxMedica, Inc."
filed_at: "2025-04-04T23:59:59+00:00"
generated_at: "2026-05-23T21:17:56.224537+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# PaxMedica board chairman Weisman and two directors resign amid PRV acquisition transition

## Summary
- Howard J. Weisman resigns as chairman but remains CEO; Karen LaRochelle and John Coelho resign from board.
- All resignations effective April 2, 2025, in connection with the previously disclosed transaction with PRV, LLC.
- No dispute or disagreement with the company or board regarding operations, policies, or practices.
- Company continues transition to becoming wholly-owned subsidiary of PRV, LLC.

## SEC filing metadata
- accession: 0001641172-25-002752
- form_type: 8-K
- cik: 0001811623
- company_name: PaxMedica, Inc.
- filed_at: 2025-04-04T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1811623/000164117225002752/0001641172-25-002752-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1811623/000164117225002752/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001641172-25-002752
- JSON: https://secwatch.observer/filing/0001641172-25-002752.json
- Plain text: https://secwatch.observer/filing/0001641172-25-002752.txt

## Key facts
- Executive change
  Karen J. LaRochelle resigned as director at PaxMedica, Inc..
  - Action: resigned
  - Role: director
  source text: In addition, directors Karen J. LaRochelle and John Coelho also resigned from the Board on that date, effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1811623/000164117225002752/0001641172-25-002752-index.htm
- Executive change
  Howard J. Weisman resigned as chairman of the Board at PaxMedica, Inc..
  - Action: resigned
  - Role: chairman of the Board
  source text: On April 2, 2025, Howard J. Weisman, chairman of the Board of Directors (the “Board”) of PaxMedica, Inc., a Delaware corporation (the “Company”), tendered his resignation from that role effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1811623/000164117225002752/0001641172-25-002752-index.htm
- Executive change
  John Coelho resigned as director at PaxMedica, Inc..
  - Action: resigned
  - Role: director
  source text: In addition, directors Karen J. LaRochelle and John Coelho also resigned from the Board on that date, effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1811623/000164117225002752/0001641172-25-002752-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.