---
schema_version: "secwatch.filing_event.v1"
accession: "0001641172-25-005772"
form_type: "8-K"
ticker: "MIRA"
cik: "0001904286"
company_name: "MIRA PHARMACEUTICALS, INC."
filed_at: "2025-04-23T23:59:59+00:00"
generated_at: "2026-05-23T08:25:06.009870+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# MIRA Pharmaceuticals' topical Ketamir-2 shows successful drug release in IVRT study

## Summary
- Topical Ketamir-2 demonstrated dose-proportional release in in vitro release testing, enabling non-opioid pain therapy.
- Preclinical efficacy studies in inflammatory and neuropathic pain models to begin shortly.
- Company evaluating Fast Track designation with FDA; U.S. topical pain relief market projected >$11.5B in 2025.
- Oral Ketamir-2 in Phase 1 trial; Phase 2a for diabetic neuropathy expected later in 2025.

## SEC filing metadata
- accession: 0001641172-25-005772
- form_type: 8-K
- ticker: MIRA
- cik: 0001904286
- company_name: MIRA PHARMACEUTICALS, INC.
- filed_at: 2025-04-23T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 8.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1904286/000164117225005772/0001641172-25-005772-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1904286/000164117225005772/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001641172-25-005772
- JSON: https://secwatch.observer/filing/0001641172-25-005772.json
- Plain text: https://secwatch.observer/filing/0001641172-25-005772.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.