---
schema_version: "secwatch.filing_event.v1"
accession: "0001641172-25-017046"
form_type: "8-K"
ticker: "MIRA"
cik: "0001904286"
company_name: "MIRA PHARMACEUTICALS, INC."
filed_at: "2025-06-30T23:59:59+00:00"
generated_at: "2026-05-18T14:48:09.904822+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# MIRA reports SKNY-1 achieves 30% weight loss and reverses cravings in zebrafish obesity model

## Summary
- SKNY-1 reduced body weight by ~30% in six days; treated animals weighed ~10% less than healthy controls.
- Liver fat buildup reversed to healthy levels; cholesterol (LDL/HDL) normalized without disrupting metabolic balance.
- Obese animals ate 2-3x more high-calorie food; SKNY-1 dose-dependently reduced compulsive eating and food-seeking.
- Nicotine craving and seeking behavior significantly reduced; high-dose group matched healthy animal behavior.
- Leptin and ghrelin normalized; lower-dose SKNY-1 reduced elevated brain dopamine linked to reward cravings.

## SEC filing metadata
- accession: 0001641172-25-017046
- form_type: 8-K
- ticker: MIRA
- cik: 0001904286
- company_name: MIRA PHARMACEUTICALS, INC.
- filed_at: 2025-06-30T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 8.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1904286/000164117225017046/0001641172-25-017046-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1904286/000164117225017046/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001641172-25-017046
- JSON: https://secwatch.observer/filing/0001641172-25-017046.json
- Plain text: https://secwatch.observer/filing/0001641172-25-017046.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.