---
schema_version: "secwatch.filing_event.v1"
accession: "0001641172-25-020408"
form_type: "8-K"
ticker: "LIXT"
cik: "0001335105"
company_name: "LIXTE BIOTECHNOLOGY HOLDINGS, INC."
filed_at: "2025-07-21T23:59:59+00:00"
generated_at: "2026-05-18T04:58:36.347738+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Lixte appoints two new independent directors; CMO resigns effective July 31

## Summary
- Board adds Jason Sawyer and Dr. Michael Holloway as independent directors, designated by Series B Preferred Stock holders.
- Dr. Stephen Forman and Dr. Yun Yen resign from Board, will serve on Scientific Advisory Committee.
- Mr. Sawyer named Chairman of Compensation Committee and member of Audit Committee.
- Chief Medical Officer Dr. Jan Schellens resigns effective July 31, 2025; consulting agreement terminated.
- Resignations not due to any disagreement with company operations, policies, or practices.

## SEC filing metadata
- accession: 0001641172-25-020408
- form_type: 8-K
- ticker: LIXT
- cik: 0001335105
- company_name: LIXTE BIOTECHNOLOGY HOLDINGS, INC.
- filed_at: 2025-07-21T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1335105/000164117225020408/0001641172-25-020408-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1335105/000164117225020408/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001641172-25-020408
- JSON: https://secwatch.observer/filing/0001641172-25-020408.json
- Plain text: https://secwatch.observer/filing/0001641172-25-020408.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.