secwatch.observer — SEC 8-K summary ====================================== Issuer: Telomir Pharmaceuticals, Inc. (TELO) CIK: 0001971532 Form: 8-K Filed at: 2025-08-07T23:59:59+00:00 Accession: 0001641172-25-022506 Event type: other_material Sentiment: positive Materiality: 0.60 Item codes: 8.01 LLM model: deepseek-v4-flash:cloud Telomir Pharmaceuticals Announces In Vitro Data Showing Telomir-1 Inhibits Key Epigenetic Enzymes -------------------------------------------------------------------------------- - Telomir-1 inhibited JMJD3, FBXL10, and FBXL11 histone demethylase enzymes in a Eurofins Discovery study. - Overactivation of these enzymes silences tumor suppressors and activates pro-inflammatory and metabolic genes. - Telomir-1 may restore normal gene expression, supporting development in cancer, autoimmune, neurodegeneration, and metabolic disorders. - Data builds on prior results showing Telomir-1 reversed epigenetic silencing of STAT1 and TMS1 in PC3 prostate cancer xenograft models. - Company is preparing to advance Telomir-1 into IND-enabling studies. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1971532/000164117225022506/0001641172-25-022506-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1971532/000164117225022506/form8-k.htm HTML page: https://secwatch.observer/filing/0001641172-25-022506 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer