other_material
confidence high
sentiment neutral
materiality 0.40
Cocrystal Pharma showcases CDI-988 at calicivirus conference, notes FDA clearance for Phase 1b challenge study
Cocrystal Pharma, Inc.
- President/co-CEO Sam Lee presented CDI-988 Phase 1 data at 9th International Calicivirus Conference (Sept 7–11) in Banff.
- CDI-988 is a first oral antiviral candidate for norovirus, with broad-spectrum activity against GII.4 and GII.17.
- Phase 1 showed favorable safety and tolerability, with no serious adverse events.
- FDA cleared a Phase 1b human challenge study for norovirus prophylaxis/treatment; expected start before end of 2025.
- CDI-988 targets a conserved region in 3CL viral proteases, designed with Cocrystal's proprietary structure-based platform.
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