{"schema_version":"secwatch.filing_event.v1","accession":"0001641489-25-000010","form_type":"8-K","ticker":"VTVT","cik":"0001641489","company_name":"vTv Therapeutics Inc.","filed_at":"2025-03-17T23:59:59+00:00","discovered_at":"2026-05-14T18:03:04.276839+00:00","generated_at":"2026-05-24T15:44:22.806988+00:00","sec_items":["8.01","9.01"],"event_type":"regulatory","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"FDA lifts clinical hold on vTv Therapeutics' cadisegliatin Phase 3 diabetes trial","bullets":["FDA lifted clinical hold effective March 14, 2025; CATT1 trial to resume after protocol amendment.","Protocol amendment shortens trial from 12 to 6 months; primary endpoint (hypoglycemia rates) unchanged.","Hold imposed July 26, 2024 due to chromatographic signal later found to be experimental artifact; no patients dosed.","Cadisegliatin is a potential first-in-class oral adjunctive therapy to insulin for type 1 diabetes.","Company expects shorter trial to expedite initiation of larger pivotal studies for NDA submission."],"urls":{"canonical":"https://secwatch.observer/filing/0001641489-25-000010","json":"https://secwatch.observer/filing/0001641489-25-000010.json","markdown":"https://secwatch.observer/filing/0001641489-25-000010.md","text":"https://secwatch.observer/filing/0001641489-25-000010.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1641489/000164148925000010/0001641489-25-000010-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1641489/000164148925000010/vtvt-20250314.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-24T15:44:22.806988+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}