{"schema_version":"secwatch.filing_event.v1","accession":"0001650664-24-000138","form_type":"8-K","ticker":"EDIT","cik":"0001650664","company_name":"Editas Medicine, Inc.","filed_at":"2024-12-10T23:59:59+00:00","discovered_at":"2026-05-14T18:03:09.109247+00:00","generated_at":"2026-05-29T05:12:03.472902+00:00","sec_items":["5.03","7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"Editas reports positive RUBY trial data: 27/28 SCD patients VOE-free, HbF 48% at month 6","bullets":["As of Oct 29, 2024, 28 SCD patients treated; 27 VOE-free post-reni-cel; median follow-up 9.5 months.","Mean total hemoglobin increased from 9.8 g/dL at baseline to 13.8 g/dL at Month 6 (n=18).","Mean HbF percentage reached 48.1% at Month 6; F-cells >90% from Month 4; MCH-F above anti-sickling threshold.","All evaluable patients engrafted; median time to neutrophil engraftment 23 days, platelet 25 days.","Two SAEs possibly related to reni-cel reported; safety consistent with myeloablative conditioning."],"urls":{"canonical":"https://secwatch.observer/filing/0001650664-24-000138","json":"https://secwatch.observer/filing/0001650664-24-000138.json","markdown":"https://secwatch.observer/filing/0001650664-24-000138.md","text":"https://secwatch.observer/filing/0001650664-24-000138.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1650664/000165066424000138/0001650664-24-000138-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1650664/000165066424000138/edit-20241206.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-29T05:12:03.472902+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}