{"schema_version":"secwatch.filing_event.v1","accession":"0001650664-25-000077","form_type":"8-K","ticker":"EDIT","cik":"0001650664","company_name":"Editas Medicine, Inc.","filed_at":"2025-05-13T23:59:59+00:00","discovered_at":"2026-05-14T18:02:49.200682+00:00","generated_at":"2026-05-21T16:12:58.390579+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.55,"calibrated_materiality_score":0.55,"confidence":"high","headline":"Editas reports in vivo POC data for undisclosed liver target; ~70% editing in mice","bullets":["Maximal liver editing of ~70% in disease-specific mouse model using LNP-delivered CRISPR/Cas cargo.","Robust target protein upregulation with >80% reduction of disease-associated biomarker in mice.","In cynomolgus monkey hepatocytes: >50% target gene editing and >15-fold protein upregulation.","Company expects to disclose the disease target and development candidate later in 2025.","Data presented at ASGCT Annual Meeting; additional oral presentation at TIDES USA on May 21."],"urls":{"canonical":"https://secwatch.observer/filing/0001650664-25-000077","json":"https://secwatch.observer/filing/0001650664-25-000077.json","markdown":"https://secwatch.observer/filing/0001650664-25-000077.md","text":"https://secwatch.observer/filing/0001650664-25-000077.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1650664/000165066425000077/0001650664-25-000077-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1650664/000165066425000077/edit-20250513.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-21T16:12:58.390579+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}