other material
confidence high
sentiment positive
materiality 0.70
Palatin initiates Phase 2 study of bremelanotide/PDE5i combo for ED non-responders
PALATIN TECHNOLOGIES INC
- Approximately 30–40% of ED patients do not respond to PDE5i monotherapy.
- Phase 2 trial of bremelanotide co-formulated with a PDE5i expected to start Q4 2023.
- Published data show synergy between bremelanotide and PDE5i via distinct mechanisms.
- Bremelanotide is the active agent in Vyleesi, approved for HSDD in women.
- Palatin successfully co-formulated bremelanotide with a PDE5i for single injection.