other material
confidence high
sentiment positive
materiality 0.75
BARDA selects Edesa's paridiprubart for U.S. government-funded Phase 2 ARDS trial
Edesa Biotech, Inc.
- Paridiprubart (EB05) chosen by BARDA for a randomized, double-blind, placebo-controlled Phase 2 platform trial in all-cause ARDS.
- Prior Phase 2 study showed paridiprubart reduced mortality by 84% among critically ill COVID-19 ARDS patients.
- Edesa's ongoing Phase 3 study of paridiprubart in COVID-19 ARDS continues in Canada and the U.S.
- BARDA contract managed via PPD (Thermo Fisher); Edesa supplies drug product and technical support.
- Goal is to label paridiprubart as standard-of-care for all-cause ARDS, with biomarker sub-study to inform development.