{"schema_version":"secwatch.filing_event.v1","accession":"0001654954-24-011975","form_type":"8-K","ticker":"CVM","cik":"0000725363","company_name":"CEL SCI CORP","filed_at":"2024-09-17T23:59:59+00:00","discovered_at":"2026-05-14T18:03:15.716965+00:00","generated_at":"2026-05-31T04:24:40.128965+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"CEL-SCI reports Multikine 5-year survival 82.6% in target head & neck cancer subgroup; HR 0.27","bullets":["Multikine showed 82.6% 5-year overall survival in target low-risk patients vs 47.3% for standard of care.","73% reduction in risk of death (HR 0.27, 95% CI [0.12-0.64], Wald p=0.0027) in that subgroup.","Data presented at ESMO 2024 support confirmatory Registration Study (212 patients) with FDA go-ahead.","Target population: newly diagnosed locally advanced head & neck cancer, no lymph node involvement, low PD-L1.","Phase 3 study subset (n=79) deemed low risk for recurrence per NCCN guidelines, not recommended chemotherapy."],"urls":{"canonical":"https://secwatch.observer/filing/0001654954-24-011975","json":"https://secwatch.observer/filing/0001654954-24-011975.json","markdown":"https://secwatch.observer/filing/0001654954-24-011975.md","text":"https://secwatch.observer/filing/0001654954-24-011975.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/725363/000165495424011975/0001654954-24-011975-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/725363/000165495424011975/cvm_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-31T04:24:40.128965+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}