other material
confidence high
sentiment positive
materiality 0.65
Arvinas updates Phase 3 vepdegestrant combo trials; VERITAC-2 topline data expected Q1 2025
ARVINAS, INC.
- Topline data for VERITAC-2 Phase 3 monotherapy trial of vepdegestrant expected in Q1 2025.
- First-line Phase 3 combo with Pfizer's atirmociclib planned for 2025; VERITAC-3 (palbociclib combo) discontinued.
- Phase 1 trial of ARV-102 (LRRK2 degrader) in Parkinson's disease initiated; data at AD/PD conference April 2025.
- Alex Santini appointed interim CCO effective Jan 17, 2025; John Northcott leaving for personal reasons.
- IND filing for KRAS G12D degrader and initial data from ARV-393 (BCL6 degrader) expected in 2025.