{"schema_version":"secwatch.filing_event.v1","accession":"0001655759-25-000147","form_type":"8-K","ticker":"ARVN","cik":"0001655759","company_name":"ARVINAS, INC.","filed_at":"2025-09-17T23:59:59+00:00","discovered_at":"2026-05-14T18:02:44.575934+00:00","generated_at":"2026-05-17T06:22:26.840438+00:00","sec_items":["2.05","7.01","8.01","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Arvinas and Pfizer to out-license vepdegestrant; cuts 15% workforce, authorizes $100M buyback","bullets":["Plans to out-license vepdegestrant commercialization rights to a third party; PDUFA date June 5, 2026.","Additional workforce reduction of 15%; expects $4.5M severance costs in Q3/Q4 2025.","Total annual cost savings expected to exceed $100M compared to FY 2024, including prior actions.","Board authorized up to $100M share repurchase program; funded by working capital, no time limit.","Reaffirms cash runway into H2 2028; three Phase 1 PROTAC degraders (ARV-102, ARV-393, ARV-806) advancing."],"urls":{"canonical":"https://secwatch.observer/filing/0001655759-25-000147","json":"https://secwatch.observer/filing/0001655759-25-000147.json","markdown":"https://secwatch.observer/filing/0001655759-25-000147.md","text":"https://secwatch.observer/filing/0001655759-25-000147.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1655759/000165575925000147/0001655759-25-000147-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1655759/000165575925000147/arvn-20250917.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T06:22:26.840438+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}