secwatch.observer — SEC 8-K summary ====================================== Issuer: C4 Therapeutics, Inc. (CCCC) CIK: 0001662579 Form: 8-K Filed at: 2023-02-23T23:59:59+00:00 Accession: 0001662579-23-000040 Event type: earnings Sentiment: negative Materiality: 0.90 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 C4 Therapeutics Reports Q4 and Full Year 2022 Financial Results with Net Loss of $128.2M and Cash Runway to End of 2024 -------------------------------------------------------------------------------- - Revenue for 2022 was $31.1M, down from $45.8M in 2021, primarily due to one-time recognition in prior year from Roche agreement termination. - Net loss for 2022 was $128.2M ($2.62 per share) compared to $83.9M ($1.82 per share) in 2021, driven by increased R&D and G&A expenses. - Cash, cash equivalents and marketable securities totaled $337.1M as of Dec 31, 2022, expected to fund operations through end of 2024. - Phase 1 dose escalation data for CFT7455 (multiple myeloma) and CFT8634 (synovial sarcoma) expected in second half of 2023. - IND submission for CFT8919 (EGFR L858R degrader) on track for first half of 2023; CFT1946 Phase 1/2 trial dosing first patient in January 2023. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1662579/000166257923000040/0001662579-23-000040-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1662579/000166257923000040/cccc-20230223.htm HTML page: https://secwatch.observer/filing/0001662579-23-000040 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer