other_material
confidence high
sentiment positive
materiality 0.55
Keros reports KER-065 Phase 1 data: BMD improvements sustained to Day 141
Keros Therapeutics, Inc.
- Phase 1 trial in healthy males showed no dose-limiting toxicities or serious adverse events.
- Whole body BMD improved at Day 85 and was sustained through Day 141 (three months post-last dose).
- Lumbar spine BMD increased after three doses and remained elevated through Day 141.
- Bone biomarker changes indicated increased formation and reduced resorption, consistent with tissue-level effects.
- Data presented at ASBMR 2025 support potential in Duchenne muscular dystrophy and bone disorders.
item 8.01item 9.01