---
schema_version: "secwatch.filing_event.v1"
accession: "0001683168-23-000454"
form_type: "8-K"
ticker: "ZSQR"
cik: "0001759186"
company_name: "Z Squared Inc."
filed_at: "2023-01-31T23:59:59+00:00"
generated_at: "2026-06-20T05:34:34.795136+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Coeptis enters sponsored research agreement with Univ. of Pittsburgh for SNAP-CAR HER2 pre-clinical work

## Summary
- Sponsored research agreement with University of Pittsburgh to advance SNAP-CAR T cells targeting HER2-positive cancers.
- Pre-clinical work will support IND filing for clinical trials, initially targeting ovarian cancer.
- Research led by Dr. Lohmueller and Dr. Deiters; IQVIA to assist as CRO for lead candidate selection.
- HER2 overexpressed in ~28% of ovarian cancer and ~25% of breast cancer cases, per the press release.

## SEC filing metadata
- accession: 0001683168-23-000454
- form_type: 8-K
- ticker: ZSQR
- cik: 0001759186
- company_name: Z Squared Inc.
- filed_at: 2023-01-31T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1759186/000168316823000454/0001683168-23-000454-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1759186/000168316823000454/coeptis_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001683168-23-000454
- JSON: https://secwatch.observer/filing/0001683168-23-000454.json
- Plain text: https://secwatch.observer/filing/0001683168-23-000454.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.