{"schema_version":"secwatch.filing_event.v1","accession":"0001683168-24-008833","form_type":"8-K","ticker":"PHIO","cik":"0001533040","company_name":"Phio Pharmaceuticals Corp.","filed_at":"2024-12-19T23:59:59+00:00","discovered_at":"2026-05-14T18:03:08.716951+00:00","generated_at":"2026-05-29T01:37:37.142668+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Phio Pharmaceuticals announces SMC recommendation to escalate to third dose cohort in PH-762 Phase 1b trial","bullets":["Safety Monitoring Committee reviewed safety data from second dose cohort and recommended escalation to next dose concentration.","First two patients in second cohort showed complete response (100% tumor clearance) and partial response (90% clearance) at Day 36.","No dose-limiting toxicities or serious adverse events reported in participants receiving intratumoral PH-762.","PH-762 is being studied for cutaneous squamous cell carcinoma, melanoma, and Merkel cell carcinoma in Phase 1b trial."],"urls":{"canonical":"https://secwatch.observer/filing/0001683168-24-008833","json":"https://secwatch.observer/filing/0001683168-24-008833.json","markdown":"https://secwatch.observer/filing/0001683168-24-008833.md","text":"https://secwatch.observer/filing/0001683168-24-008833.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1533040/000168316824008833/0001683168-24-008833-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1533040/000168316824008833/phio_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud","generated_at":"2026-05-29T01:37:37.142668+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}