secwatch.observer — SEC 8-K summary ====================================== Issuer: Praxis Precision Medicines, Inc. (PRAX) CIK: 0001689548 Form: 8-K Filed at: 2023-02-07T23:59:59+00:00 Accession: 0001689548-23-000043 Event type: earnings Sentiment: neutral Materiality: 0.50 Item codes: 2.02, 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Praxis reports FY2022 net loss $214M; cash $100.5M, runway into 1Q24 -------------------------------------------------------------------- - Cash and investments $100.5M as of Dec 31, 2022, down from $275.9M; expected to fund ops into 1Q24. - Net loss FY2022 $214.0M vs $167.1M; Q4 net loss $41.2M. - R&D expense FY2022 $155.0M, up from $120.3M, reflecting Cerebrum/Solidus platform spending. - Phase 2b ulixacaltamide topline results for essential tremor expected in 1Q23. - Entered UCB collaboration for KCNT1 program; up to ~$100M in milestones plus royalties. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1689548/000168954823000043/0001689548-23-000043-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1689548/000168954823000043/prax-20230207.htm HTML page: https://secwatch.observer/filing/0001689548-23-000043 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer