other material
confidence high
sentiment positive
materiality 0.70
Serina presents non-immunogenic POZ-lipid data at ACS 2025 meeting
Serina Therapeutics, Inc.
- Randall Moreadith, M.D., Ph.D., Chief Development Officer, presented at ACS Spring 2025 in San Diego.
- Presentation titled 'A Non-Immunogenic LNP for Gene Delivery: Characterization of Poly(oxazoline) Lipid Nanoparticles'.
- In rats, POZ-lipid did not trigger IgM or IgG antibody response after repeat dosing.
- In contrast, PEG-lipid standards elicited a strong and boosted antibody response.
- Non-immunogenic POZ-lipid could enable safer LNP formulations for gene therapy and RNA medicines.