other material
confidence high
sentiment positive
materiality 0.60
Serina's SER-252 Phase 1b Cohort 1 clears safety review; advances to Cohort 2
Serina Therapeutics, Inc.
- Independent Safety Monitoring Committee recommended advancing SER-252 to Cohort 2 after blinded review of Cohort 1 safety/tolerability data.
- Cohort 1 (lowest dose, n=8) showed sustained apomorphine exposure and motor function improvements in individual patients.
- Topline data from single-ascending-dose portion expected in first half of 2027.
- Study is randomized, double-blind, placebo-controlled; 5 cohorts of 8 in SAD portion, then MAD portion.