Krystal Biotech shareholders approve all four proposals at 2026 annual meeting

The Company’s stockholders elected Krish S. Krishnan and Christopher Mason as members of the Company’s Board of Directors as Class III directors for a three-year term. The results of the vote were as follows: Nominee Votes For Votes Withheld Broker Non-Votes Krish S. Krishnan 23,802,920 3,079,194 1,581,473 Christopher Mason 22,581,854 4,300,260 1,581,473

The Company’s unaffiliated stockholders (i.e., excluding the members of the the Company’s board of directors and the defendants in the litigation entitled Corbin v. Janney, et al. , C.A. No. 2025-1051-KSJM (Del. Ch.) who refrained from voting on this matter in their capacities as stockholders) approved the Company’s Non-Employee Director Compensation Policy. The results of the vote were as follows: Votes For Votes Against Abstentions Broker Non-Votes 21,374,021 2,349,550 3,158,543 1,581,473

The Company’s stockholders approved, on an advisory (non-binding) basis, the compensation of the Company’s named executive officers for the fiscal year ended December 31, 2025, as disclosed in the Company’s proxy statement for the Annual Meeting pursuant to the compensation disclosure rules of the Securities and Exchange Commission. The results of the vote were as follows: Votes For Votes Against Abstentions Broker Non-Votes 25,679,318 1,195,788 7,008 1,581,473

The Company’s stockholders ratified the appointment of KPMG LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2026. The results of the vote were as follows: Votes For Votes Against Abstentions 28,443,155 15,434 4,998