{"schema_version":"secwatch.filing_event.v1","accession":"0001711279-26-000050","form_type":"8-K","ticker":"KRYS","cik":"0001711279","company_name":"Krystal Biotech, Inc.","filed_at":"2026-07-21T21:24:31+00:00","discovered_at":"2026-07-21T21:26:00.308293+00:00","generated_at":"2026-07-21T21:26:06.062273+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.5,"calibrated_materiality_score":0.5,"confidence":"high","headline":"Krystal Biotech discloses single-patient data from discontinued KB801 study in patent response","bullets":["Filed response to USPTO Office Action for KB801 patent application; included data from one patient in discontinued clinical study.","Patient experienced complete closure of persistent corneal epithelial defect after KB801 treatment.","Study discontinued to advance KB801 into pivotal trial; no safety concerns or serious adverse events observed.","Company cautions that single-patient observation is not top-line results and no conclusions on safety/efficacy should be drawn.","Pivotal trial results for KB801 expected to be reported in ordinary course."],"urls":{"canonical":"https://secwatch.observer/filing/0001711279-26-000050","json":"https://secwatch.observer/filing/0001711279-26-000050.json","markdown":"https://secwatch.observer/filing/0001711279-26-000050.md","text":"https://secwatch.observer/filing/0001711279-26-000050.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1711279/000171127926000050/0001711279-26-000050-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1711279/000171127926000050/krys-20260721.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-07-21T21:26:06.062273+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}