earnings
confidence high
sentiment negative
materiality 0.60
Denali Q3 net loss widens to $103.3M; cash at $1.11B after $296M offering
Denali Therapeutics Inc.
2022-Q3 EPS reported
-$1.85
revenue$98,180,000
- Net loss of $103.3M for Q3 2022 vs. $84.6M in Q3 2021; collaboration revenue fell to $3.6M from $5.3M.
- R&D expenses rose to $87.8M (up $16.2M) driven by LRRK2 milestone payment and pipeline progress.
- Cash, cash equivalents, and marketable securities totaled $1.11B as of Sep 30, 2022, plus net proceeds of $296.2M from Oct 2022 public offering.
- Phase 3 LIGHTHOUSE study of BIIB122 initiated in LRRK2-positive Parkinson's; Phase 2 COMPASS study of DNL310 enrolling in Hunter syndrome.
- Interim Phase 1 data for TAK-594/DNL593 showed substantial CSF progranulin increases supporting FTD-GRN Part B dosing.