earnings
confidence high
sentiment neutral
materiality 0.70
Arcus Q4 net loss $81M; cash to $1.2B after Gilead; streamlines TIGIT program; casdatifan shows promise
Arcus Biosciences, Inc.
2023-FY EPS reported
-$4.15
revenue$117,000,000
- Net loss of $81M in Q4 2023 ($307M full year); revenue $31M Q4 2023 vs $34M Q4 2022.
- Pro forma cash $1.2B after $320M equity investment from Gilead in Jan 2024; funding into 2027.
- Discontinued ARC-10 Phase 3 in PD-L1-high NSCLC; accelerating STAR-121; planning STAR-131 in perioperative NSCLC.
- Casdatifan (HIF-2a) Phase 1 data: 20 mg dose achieved similar EPO suppression as 120 mg belzutifan; no DLTs.
- Quemliclustat in pancreatic cancer: median OS 15.7 months in pooled ARC-8 analysis; Phase 3 planned early 2025.