other_material
confidence high
sentiment positive
materiality 0.65
Arcus reports 46% confirmed ORR for casdatifan + cabozantinib in ccRCC post-immunotherapy
Arcus Biosciences, Inc.
- Phase 1/1b ARC-20 interim analysis shows 46% cORR (11/24) per RECIST v1.1; median follow-up 5.3 months.
- Response includes 1 complete response (4%) and 10 partial responses (42%); 50% had stable disease.
- Safety evaluable population (n=42) showed acceptable safety profile with no new unexpected risks or overlapping toxicity.
- Study evaluates casdatifan 100mg QD plus cabozantinib 60mg QD in patients with ccRCC who progressed on prior immunotherapy.
item 7.01item 8.01