other material
confidence high
sentiment positive
materiality 0.65
Zentalis Q3 cash $421.7M, ZN-c3 dose optimization extends USC trial; Cyclin E biomarker strategy set
Zentalis Pharmaceuticals, Inc.
- Cash $421.7M as of Sep 30, 2022; runway into Q1 2025.
- R&D expenses $42.2M (down 22% YoY); G&A $12.0M (up 35% YoY).
- ZN-c3 dose optimization extends USC trial timeline; update expected H1 2023.
- Cyclin E amplification/overexpression selected as biomarker for ZN-c3 monotherapy in ovarian cancer.
- Appointed new CMO (Carrie Brownstein), CSO (Kevin Bunker), CTO (Mark Lackner); added board member Jan Skvarka.