earnings
confidence high
sentiment neutral
materiality 0.65
Zentalis reports FY2023 cash $483M, azenosertib ORR 37%, appoints CMO/CBO
Zentalis Pharmaceuticals, Inc.
2023-FY EPS reported
-$4.47
- Cash, equivalents and securities $482.9M at Dec 31, 2023; runway into 2026; plus $35M upfront from Immunome in Jan 2024.
- R&D expenses $189.6M (up 9.8%), G&A $64.4M (up 18%) versus FY2022.
- Azenosertib Phase 1 monotherapy showed 37% ORR and 6.5-month mPFS in platinum-resistant ovarian/USC cancer patients.
- Appointed Diana Hausman, M.D., as CMO and Kyle Rasbach, Ph.D., Pharm.D., as CBO.
- NDA submission for azenosertib in gynecologic malignancy targeted for 2026; multiple data readouts in 2024-2025.