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confidence high
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materiality 0.90
Anavex Life Sciences announces positive Phase 2b/3 trial results for ANAVEX2-73 in Alzheimer's disease
ANAVEX LIFE SCIENCES CORP.
- Trial met primary endpoints ADAS-Cog and ADCS-ADL with statistically significant results (p=0.033 and p=0.0255).
- Key secondary endpoint CDR-SB also met (p=0.040), showing 27% reduction in clinical decline.
- Patients treated with ANAVEX2-73 were 84% more likely to have improved cognition vs placebo (Odds Ratio=1.84).
- ANAVEX2-73 demonstrated 45% reduction in cognitive decline measured by ADAS-Cog compared to placebo.
- Company plans to meet with regulatory authorities to discuss next steps for approval.