---
schema_version: "secwatch.filing_event.v1"
accession: "0001746473-25-000179"
form_type: "8-K"
ticker: "PLRX"
cik: "0001746473"
company_name: "PLIANT THERAPEUTICS, INC."
filed_at: "2025-12-08T23:59:59+00:00"
generated_at: "2026-05-16T13:59:44.483972+00:00"
event_type: "leadership"
sentiment: "negative"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Pliant Therapeutics CMO Éric Lefebvre to depart on Dec 15, 2025

## Summary
- Chief Medical Officer Éric Lefebvre's employment terminates effective Dec 15, 2025.
- Lefebvre expected to assist as consultant post-Separation Date for transition support.
- No immediate replacement for CMO role announced by the Company.

## SEC filing metadata
- accession: 0001746473-25-000179
- form_type: 8-K
- ticker: PLRX
- cik: 0001746473
- company_name: PLIANT THERAPEUTICS, INC.
- filed_at: 2025-12-08T23:59:59+00:00
- event_type: leadership
- sentiment: negative
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1746473/000174647325000179/0001746473-25-000179-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1746473/000174647325000179/plrx-20251202.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001746473-25-000179
- JSON: https://secwatch.observer/filing/0001746473-25-000179.json
- Plain text: https://secwatch.observer/filing/0001746473-25-000179.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.